Thermo Scientific NanoDrop One Microvolume UV Vis Spectrophotometer

The Thermo Scientific NanoDrop One Spectrophotometer is a compact, stand-alone UV-visible spectrophotometer for measurement of highly concentrated samples across a wide variety of analytes without the need for dilution. A glove-compatible touchscreen offers easy access to preloaded software applications and enables purity and concentration assessments in seconds. Built-in Acclaro Sample Intelligence technology helps identify and correct for the contaminants present. Make informed decisions on sample quality and improve your success in downstream applications with NanoDrop technology.

Pioneering pedestal technology

Simply pipet a drop of your DNA, RNA, or protein sample on the pedestal and pull down the arm; results appear in seconds

Advanced sample intelligence

By analyzing absorbance across the full spectrum, Acclaro Sample Intelligence software can identify contaminants and correct quantitation results before you use them in downstream applications

Rapid time to results

Results appear within seconds of initiating a measurement, and Auto-Blank and Auto-Measure settings can further streamline your workflow

Tiny sample sizes

Requires only 1–2 µL of sample without dilution, even for highly concentrated samples

Differentiates DNA from RNA

Acclaro software uses full-spectrum data to tease apart DNA from RNA and calculate corrected nucleic acid concentrations

Your dependable lab partner

Since their introduction in 2001, NanoDrop spectrophotometers have become indispensable in many labs, accumulating over 55,000 scientific citations

In addition, the NanoDrop One Spectrophotometer offers indispensable features that make it a reliable, easy-to-use laboratory workhorse for many sample and assay types, including regulated environments. To learn more, see the sections below.

Expanded dynamic range

Measure up to 27,500 ng/µL dsDNA or 400 mg/mL IgG without dilution

Streamlined multi-sample processing

With instant Auto-Measure and Auto-Blank capabilities

Advanced connectivity

Connect, export, print, and view data remotely

Optional security software for compliance

Security Suite software aids compliance with FDA 21 CFR Part 11 electronic recordkeeping regulations

Wide spectral range

Measure the full UV-Vis spectrum from 190–850 nm, allowing a range of assays as shown in the table below

Routine and custom embedded applications

DNA, RNA, and protein quantification, full spectral data, purity ratios (A260/A280, A260/A230), and more

Local or PC control software

Operate your instrument from the glove-compatible touchscreen or your Ethernet-connected PC, including custom methods and data export capabilities

Onboard integrated Learning Center

A repository of technical support documents and educational animations at your fingertips